First, molecular hydrogen (H2) is an extraordinary antioxidant, a free radical quencher that selectively scavenges the most dangerous and destructive hydroxyl radicals. Hydroxyl radicals initiate their cycle of destruction by stealing electrons from molecules in DNA, proteins, and fats, destabilizing them and setting off a chain reaction of oxidative stress.
H2 readily gives up electrons to hydroxyl radicals, which stabilizes them and stops them in their tracks. It also reduces the toxicity of peroxynitrite, another destructive oxidant, and further boosts the body’s defenses by increasing production of natural antioxidants such as glutathione, superoxide dismutase, and catalase.
Second, H2 has beneficial effects on cell signaling and gene expression. It suppressesTNF-alpha and other proteins involved in inflammation and turns on mechanisms that protect against cell death. But because H2 is selective, it does not scavenge essential redox signaling radicals that play a key role as cellular messengers.
Third, recent studies show that H2-infused water increases the production of a hormone called ghrelin. Secreted in the stomach, ghrelin is best known for stimulating appetite, but it also boosts growth hormone release and has protective effects in the brain, vascular system, liver, and elsewhere.
Fourth, H2 “nano” molecules are able to diffuse through cellular membranes, enter the mitochondria and nucleus of cells, cross the blood-brain barrier, and exert their positive effects in tissues and organs throughout the body.
Therefore, it’s not surprising that benefits of H2 therapy have been demonstrated in animal models and/or human studies in a wide range of conditions, including traumatic brain and spinal cord injuries, Parkinson’s, Alzheimer’s, strokes, heart attacks, vascular disease, diabetes, liver and kidney disorders, autoimmune conditions, and lung problems.
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